|
|
S-adenosyl-L-methionine <=> H+ + nicotianamine + S-methyl-5''-thioadenosine
|
2.5.1.43
nicotianamine synthase
|
–
|
|
BRENDA:
BR47667
KEGG:
R00075
MetaCyc:
2.5.1.43-RXN
|
|
|
|
S-ribosylhomocysteine <=> L-homocysteine + (S)-4,5-dihydroxypentan-2,3-dione
|
4.4.1.21
S-ribosylhomocysteine lyase
|
–
|
|
BRENDA:
BR48539;
BS371157
KEGG:
R01291
MetaCyc:
RIBOSYLHOMOCYSTEINASE-RXN
SABIO-RK:
6873
|
|
|
|
L-homocysteine + betaine <=> L-methionine + N,N-dimethylglycine
|
2.1.1.5
betaine---homocysteine S-methyltransferase
|
–
|
|
BRENDA:
BR40558
KEGG:
R02821
MetaCyc:
2.1.1.5-RXN
SABIO-RK:
2687
|
|
|
|
5-(methylthio)-2,3-dioxopentyl_phosphate <=> H+ + 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl_phosphate
|
3.1.3.77
acireductone synthase
4.1.1.39
ribulose-bisphosphate carboxylase
4.2.1.11
phosphopyruvate hydratase
5.3.2.5
2,3-diketo-5-methylthiopentyl-1-phosphate enolase
|
–
–
–
–
|
|
BRENDA:
BR48754
KEGG:
R07393
MetaCyc:
R82-RXN
|
|
|
|
S-methyl-5''-thioadenosine + phosphate <=> adenine + S-methyl-5-thio-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
3.2.2.9
adenosylhomocysteine nucleosidase
|
–
–
–
|
|
BRENDA:
BR47472;
BS354415
KEGG:
R01402
MetaCyc:
5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN
SABIO-RK:
1594
|
|
|
|
S-methyl-5''-thioadenosine + H2O <=> 5-methylthioribose + adenine
|
3.2.2.16
methylthioadenosine nucleosidase
3.2.2.9
adenosylhomocysteine nucleosidase
|
–
–
|
|
BRENDA:
BR19228;
BR53084
KEGG:
R01401
MetaCyc:
METHYLTHIOADENOSINE-NUCLEOSIDASE-RXN
SABIO-RK:
1593
|
|
|
|
L-homoserine + succinyl-CoA <=> O-succinyl-L-homoserine + CoA
|
2.3.1.46
homoserine O-succinyltransferase
|
–
|
|
BRENDA:
BR44047
KEGG:
R01777
MetaCyc:
HOMSUCTRAN-RXN
|
|
|
|
O-succinyl-L-homoserine + L-cysteine <=> L-cystathionine + succinate + H+
|
2.5.1.48
cystathionine gamma-synthase
|
–
|
|
BRENDA:
BR47465
KEGG:
R02508;
R03260
MetaCyc:
O-SUCCHOMOSERLYASE-RXN
SABIO-RK:
3081
|
|
|
|
L-methionine + H2O <=> methanethiol + 2-oxobutyrate + NH3
|
4.4.1.11
methionine gamma-lyase
|
–
|
|
BRENDA:
BR3437
KEGG:
R00654
MetaCyc:
METHIONINE-GAMMA-LYASE-RXN
SABIO-RK:
1038
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> L-methionine_(R)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.14
L-methionine (R)-S-oxide reductase
1.8.4.B3
|
–
–
–
–
|
|
BRENDA:
BR48616
KEGG:
R07608
MetaCyc:
1.8.4.14-RXN
|
|
|
|
L-cysteine + O-phospho-L-homoserine <=> L-cystathionine + phosphate
|
2.5.1.48
cystathionine gamma-synthase
|
–
|
|
BRENDA:
BS354338
MetaCyc:
CYSPH-RXN
SABIO-RK:
13007
|
|
|
|
ATP + L-methionine + H2O <=> S-adenosyl-L-methionine + phosphate + diphosphate
|
2.5.1.6
methionine adenosyltransferase
|
–
|
|
BRENDA:
BR47590
KEGG:
R00177
MetaCyc:
S-ADENMETSYN-RXN
SABIO-RK:
96
|
|
|
|
S-adenosyl-L-methionine + L-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine + H+
|
2.1.1.10
homocysteine S-methyltransferase
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
2.1.1.280
selenocysteine Se-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BS289526;
BS419713
KEGG:
R00650
MetaCyc:
HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN
SABIO-RK:
1035
|
|
|
|
L-cystathionine + H2O <=> L-homocysteine + pyruvate + NH3
|
2.5.1.48
cystathionine gamma-synthase
3.5.1.61
mimosinase
4.2.1.22
cystathionine beta-synthase
4.4.1.1
cystathionine gamma-lyase
4.4.1.13
cysteine-S-conjugate beta-lyase
4.4.1.28
L-cysteine desulfidase
4.4.1.3
dimethylpropiothetin dethiomethylase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR3446
KEGG:
R01286
MetaCyc:
CYSTATHIONINE-BETA-LYASE-RXN
SABIO-RK:
1500;
1501
|
|
|
|
ATP + 5-methylthioribose <=> H+ + ADP + S-methyl-5-thio-alpha-D-ribose_1-phosphate
|
2.7.1.100
S-methyl-5-thioribose kinase
|
–
|
|
BRENDA:
BR47714;
BS356940
KEGG:
R04143
MetaCyc:
5-METHYLTHIORIBOSE-KINASE-RXN
SABIO-RK:
3864
|
|
|
|
elongator_tRNAMet + L-methionine + ATP <=> L-methionyl-[elongator_tRNAMet] + diphosphate + AMP
|
6.1.1.10
methionine---tRNA ligase
|
–
|
|
BRENDA:
BR40
KEGG:
R03659
MetaCyc:
METHIONINE--TRNA-LIGASE-RXN
SABIO-RK:
355
|
|
|
|
S-adenosyl-L-homocysteine + H2O <=> S-ribosylhomocysteine + adenine
|
3.2.2.16
methylthioadenosine nucleosidase
3.2.2.30
aminodeoxyfutalosine nucleosidase
3.2.2.9
adenosylhomocysteine nucleosidase
|
–
–
–
|
|
BRENDA:
BR19231
KEGG:
R00194
MetaCyc:
ADENOSYLHOMOCYSTEINE-NUCLEOSIDASE-RXN
|
|
|
|
5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate + L-homocysteine <=> tetrahydropteroyl-Glu3 + L-methionine
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
|
BRENDA:
BR40568
KEGG:
R04405
MetaCyc:
HOMOCYSMET-RXN
|
|
|
|
L-homocysteine + 5-methyltetrahydrofolate <=> L-methionine + tetrahydrofolate
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
|
BRENDA:
BR40552
KEGG:
R00946
MetaCyc:
HOMOCYSMETB12-RXN
SABIO-RK:
1260
|
|
|
|
S-methyl-5-thio-D-ribulose_1-phosphate <=> 5-(methylthio)-2,3-dioxopentyl_phosphate + H2O
|
4.2.1.109
methylthioribulose 1-phosphate dehydratase
|
–
|
|
BRENDA:
BR48756
KEGG:
R07392
MetaCyc:
R145-RXN
|
|
|
|
S-adenosyl-L-methionine + DNA <=> S-adenosyl-L-homocysteine + DNA_containing_5-methylcytosine
|
2.1.1.37
DNA (cytosine-5-)-methyltransferase
|
–
|
|
BRENDA:
BS319681
KEGG:
R00380
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> H+ + 4-methylsulfanyl-2-oxobutanoate + formate
|
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
|
|
BRENDA:
BR48660
KEGG:
R07364
MetaCyc:
R147-RXN
|
|
|
|
L-methionine + H2O + O2 <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
|
1.13.12.9
phenylalanine 2-monooxygenase
1.4.3.2
L-amino-acid oxidase
|
–
–
|
|
BRENDA:
BS259010
KEGG:
R00648
SABIO-RK:
1033
|
|
|
|
2-hydroxy-5-(methylthio)-3-oxopent-1-enyl_phosphate + H2O <=> 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate
|
3.1.3.77
acireductone synthase
3.1.3.87
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase
|
–
–
|
|
BRENDA:
BR48755
KEGG:
R07394
MetaCyc:
R83-RXN
|
|
|
|
S-adenosyl-L-methionine + H2O <=> adenosine + L-methionine + H+
|
2.5.1.B21
3.13.1.8
S-adenosyl-L-methionine hydrolase (adenosine-forming)
|
–
–
|
|
BRENDA:
BR49470
KEGG:
R12098
MetaCyc:
RXN-19155
|
|
|
|
S-adenosyl-L-homocysteine + H2O <=> L-homocysteine + adenosine
|
3.3.1.1
adenosylhomocysteinase
|
–
|
|
BRENDA:
BR16046
KEGG:
R00192
MetaCyc:
ADENOSYLHOMOCYSTEINASE-RXN
SABIO-RK:
738;
8119
|
|
|
|
S-methyl-5-thio-alpha-D-ribose_1-phosphate <=> S-methyl-5-thio-D-ribulose_1-phosphate
|
5.3.1.23
S-methyl-5-thioribose-1-phosphate isomerase
|
–
|
|
BRENDA:
BR230;
BS1040
KEGG:
R04420
MetaCyc:
5.3.1.23-RXN
|
|
|
|
S-adenosyl-L-methionine + H+ <=> CO2 + S-adenosylmethioninamine
|
4.1.1.19
arginine decarboxylase
4.1.1.50
adenosylmethionine decarboxylase
|
–
–
|
|
BRENDA:
BR310
KEGG:
R00178
MetaCyc:
SAMDECARB-RXN
SABIO-RK:
731
|
|
|
|
L-methionine + phenylpyruvate <=> 4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
|
2.6.1.14
asparagine---oxo-acid transaminase
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.58
phenylalanine(histidine) transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS353571
MetaCyc:
RXN-7708
SABIO-RK:
11201
|
|